Meriden Smartflor 4%

Meriden Smartflor 4% offers an effective yet economical solution for bacteria-related Swine Respiratory Diseases (SRD) and severe diarrhoea caused by E. coli and Salmonella spp. in pig herds.

A fast-acting, synthetic feed-grade antibiotic containing florfenicol 40 mg/g that enables mass-medication for control of respiratory diseases associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus spp., Streptococcus suis, Bordetella bronchiseptica and Mycoplasma hyopneumoniae.

It has broad spectrum activities that are primarily bacteriostatic and its effect is on both Gram-positive and Gram-negative bacteria, as well as mycoplasma.

How does Meriden Smartflor 4% work?

Meriden Smartflor 4% binds to the ribosomes of the susceptible bacteria, preventing bacterial protein formation. It does this by inhibiting peptidyl transferase activity, which is necessary for transferring amino acids to peptide chains for bacterial protein formation. Hence, bacteria are unable to synthesise protein.

Despite being a fluorinated derivative of chloramphenicol, it does not carry the risk of inducing human aplastic anaemia that is associated with the use of chloramphenicol, yet it has activity against some chloramphenicol-resistant strains of bacteria. This is because of the structural presence of a p-methyl sulfonyl group instead of the p-nitro group and the presence of a fluorine atom instead of the hydroxyl group in the terminal primary alcohol function of chloramphenicol.

Why use Meriden Smartflor 4%?

  Fast acting

  Controls severe diarrhoea caused by E. coli and Salmonella spp.

  Increases average daily weight gain

  Increases survivability

  Highly palatable

  Can be incorporated into pelleted feeds

Efficacy of Florfenicol Premix in Weaning Pigs Experimentally Infected with Actinobacillus pleuropneumoniae

Palacios-Arriaga JM, Gutierrez-Pabello JA, Chavez-Gris G, Hernandez-Castro R

This study demonstrated that medication with feed containing 40 ppm of florfenicol efficiently blocked the development of signs and lesions of pleuropneumonia caused by A. pleuropneumoniae and doubled the average daily body weight gain.

Administration to breeding animals, particularly boars is not recommended.
Effects on reproductive performance and pregnancy have not been determined.

Storage and stability
Close pack after use.
Store product in a dry, cool area away from direct sunlight.
Use within 12 months from opening. In formulated feeds use within 6 months from mixing.